
COMBINE WEAPONS in the microscopic roguelite turret shooter with macroscopic depth. Survive 6 modes using an astounding array of turrets, perks, mutations and power-ups on this psychedelic journey to the heart of the abyss. Shmup Mode turns it into a vertical shoot 'em up!
Modeled estimate, not a reported figure. How we estimate →
Discounts
Every price cut of more than 20% we have observed, in each market that quoted one, with this game's chart position on either side of it. These are episodes, not a model: a sale is one event, and one event cannot tell you what the next one will do.
Reviews, worldwide (the counter carries no country): 0/day in the week to Aug 28 → 0.14/day in the week after.
Reviews, worldwide (the counter carries no country): 19/day in the week to Jul 16 → 0.14/day in the week after.
For scale, across Steam · Top Sellers · Brazil over the last 30 days: the 26 chart moves that followed a price cut of more than 20% went a median of 7 places towards #1, and the 2,400 moves with no price cut behind them went 2 away. One store, one chart, one country — it is the only place we have enough observations to say even that.
Prices outside the United States have been collected since 6 August 2026 and chart positions since 19 July 2026, so a cut older than that has no market to compare and a market that joined later has no history yet. Nothing here is converted between currencies.
About
Dive into the microscopic world, radiating with bioluminescent life and unspeakable horrors. Genome Guardian is a deeply-complex shooter that's easy to pick up but hard to master. Research permanent upgrades to survive a variety of microbes across 6 game modes, each with multiple "depths".
Pair DNA nucleotides Adenine (rapidfire), Cytosine (precision), Guanine (spread), Thymine (explosive) to discover wild hybrid bioweapons!
Bomb + Shotgun combines explosives with spread to create Blast Shotgun!
Bomb + Bomb doubles down on explosive power to make Bazooka!
Blast Shotgun + Shotgun forms the all-powerful Flak Cannon!

49 Turrets with unique strengths and functions
96 Perks to mix and match that drastically change how you play
75 Weapon & Turret Mods that can turn shots into sticky laser mines or bouncing fireballs
64 Mutations alter the challenges you face each run

20-minute Runs that can be continued in Endless Mode
75 Bassy Electronic Tunes that adapt to the current mood & intensity
Cosmetics like spider legs and tank tread
Accessibility Settings for colourblindness, motion sickness, and even arachnophobia!
100 Steam Achievements
Steam Trading Cards
Cloud Save
Plays great on Steam Deck!!!

Engagement
Reviews
Themes across 45 recent reviews and how positive each mention is. A keyword signal, not full sentiment analysis.
Reviews
17 hours before I completed the "main" path and I had SO much fun doing it. This is an AMAZING game, especially if you love tinkering and optimizing; however, even though it's hard, it can totally be played casually. My first "win" (wave 30) was entirely casual, I wasn't tryharding in the slightest. Game explains more than enough with a little hint of snark (which is deserved at times, honestly) and has lots of character. [spoiler]I AM T H E GENOME GUARDIAN, YOU IN[i]SIG[b]NIFICANT[/b][/i] ♥♥♥♥![/spoiler]
Such an insanely fun game. The sheer amount of things to unlock and tweak your visuals, weapons, ship, bullets, background, music, is daunting in a good way xD
Media

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Price dynamics, follower growth, revenue and sales trajectories with interactive tooltips
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Genres
Stats
All-time low is the lowest price we've recorded for this game since we started tracking it.
Languages: English
Hours played at review time, across 46 reviews with recorded playtime.
positive critical· bar length = how often the theme comes up
Extremely fun game, Highly recommend
10/10 Unlike most games with simple art styles, Genome Guardian is just perfect. Everything you would want in a game is in this one. It is fast-paced with infinite combo potential, can be replayed basically forever, has meaningful progression between runs, and actually has a story. I'm blown away, and the low price makes it all the more worth the buy.
Not only has a staggering amount of content (I'm only now reaching the "main" difficulty level after 20 hours and have many turrets, perks, and weapons not yet unlocked), but very clearly has a lot of attention to detail in the presentation, options, and general UX. Notably, this is the first game of this general type where I haven't yet felt the need to consult a wiki or messageboards or discord etc. to check how something works or what the effects of something are, as nearly everything is communicated very simply & clearly to the player so you can make well informed choices at each step.
Never thought that some random game I get in a bundle would end up being better than the game I initially wanted to purchase, but this game is not only better than that other game but also 90% of my library and with the sequel coming out in like 2 weeks I don't know if i should continue grinding this game or stock up on research in the demo for the sequel.
This game is great! Dev: microbes spawn off the left and right screen edges if you play shmup mode on a portrait screen, leading to hits from microbes you cant see.
Yes, you will buy this game. Yes, you will love this game. I have exactly zero complaints. All the problems I do have, come from my own lack of skill or game knowledge, and it's so obvious... That's the first time a game has been so black and white about what is your fault and what is going wrong because of bad game design. I haven't seen any bad game design so far. Also, the music in here is like crack. You guys should look into expanding the track list a bit, or maybe a feature to allow our own music to kind of sync up with the game? It's a real basic visual sync that goes off just peak beats vs trying to match the whole song.
fun game LOT OF STUFF to unlock and good replayablity
Brilliant one of these, play it
Players by region
Where this game's players are, estimated from review languages.
Related
| Game | Estimated lifetime revenue | Reviews | Review score | Price |
|---|---|---|---|---|
| $1.2K | 15 | 100% | $3.50 | |
| — | 0 | — | — | |
| $570 | 3 | 67% | $7.99 | |
| $37 | 2 | 50% | $0.99 | |
| — | 0 | — | — | |
| — | 0 | — | — |
Related
| Game | Estimated lifetime revenue | Reviews | Review score | Price |
|---|---|---|---|---|
| $240.3K | 373 | 83% | $19.99 | |
| $240.4K | 450 | 61% | $14.99 | |
| $240.2K | 420 | 84% | $8.95 | |
| $240.1K | 1.7K | 85% | $12.99 | |
| $240.1K | 363 | 59% | $19.99 | |
| $240.5K | 1.4K | 65% | $4.99 |