
COMBINE WEAPONS in the microscopic shooter with macroscopic depth. BUILD YOUR NANOBOT from hundreds of parts. SURVIVE the microbial onslaught once more in this psychedelic dive to the Abyss, full of mutations, minerals, anomalies and powerup polyps. SHMUP mode turns it into a vertical shoot 'em up!
Modeled estimate, not a reported figure. How we estimate →
Discounts
Every price cut of more than 20% we have observed, in each market that quoted one, with this game's chart position on either side of it. These are episodes, not a model: a sale is one event, and one event cannot tell you what the next one will do.
Reviews, worldwide (the counter carries no country): 0.57/day in the week to Aug 29 → 1.57/day in the week after.
For scale, across Steam · Top Sellers · Brazil over the last 30 days: the 25 chart moves that followed a price cut of more than 20% went a median of 10 places towards #1, and the 2,413 moves with no price cut behind them went 2 away. One store, one chart, one country — it is the only place we have enough observations to say even that.
Prices outside the United States have been collected since 6 August 2026 and chart positions since 19 July 2026, so a cut older than that has no market to compare and a market that joined later has no history yet. Nothing here is converted between currencies.
About


Research permanent upgrades to survive a variety of microbes & modes in this massively expanded follow-up to Genome Guardian.


Make stationary turrets, psychic water sprinkler motorbikes, or maybe a dual-wielding fidget spinner Gundam.
Easily recreate your favourite turrets from the first game…or combine em' all into one frankenstein monstrosity
Save/Load 24 loadouts
Paint & Pattern customization

Shotgun + Bomb mix explosives with spread for Blast Shotgun!
SMG + Pistol make an accurate, fast-firing Scout Rifle!
Blast Shotgun + Scout Rifle = something a whole lot crazier!


20-minute runs you can save & resume at any time + improved Endless Mode
Complete side objectives during runs for extra cash
Mine mineral deposits for resources
Trigger powerful Gadget active abilities
Test discovered weapons in the Database
100 bassy electronic tunes with in-game Jukebox accessible any time + Streamer Mode
Auto aim/fire toggles

Localization in 10 languages
Full rebinding for keyboard & gamepad
400% better performance/framerate on high & low-end PCs
Accessibility for colourblindness, motion sickness & arachnophobia
100 Steam achievements
Cloud Save
Plays great on Steam Deck!
Engagement
Reviews
Themes across 101 recent reviews and how positive each mention is. A keyword signal, not full sentiment analysis.
Reviews
Exellent sequal - more of everything, well balanced & very entertaining!
I was impressed by this game from the beginning but then... I witnessed Jester guardian 🤡 I mean, the game can get visually intense and drop absolute bangers during normal play, sure. But Jester is something else - a descent to madness through total sensoric overload with extreme attention to detail. Possibly the very peak of both art and insanity. May Alpherior live long and prosper so he can share more of his genius (and insanity) with us!
Media

Related
Related
Price dynamics, follower growth, revenue and sales trajectories with interactive tooltips
This and every other Pro feature is free until October 20, 2026. A free account is all it takes.
Genres
Stats
All-time low is the lowest price we've recorded for this game since we started tracking it.
Languages: English*, French*, Italian*, German*, Spanish - Spain*, Japanese*, Korean*, Portuguese - Brazil*, Russian*, Simplified Chinese**languages with full audio support
Hours played at review time, across 101 reviews with recorded playtime.
positive critical· bar length = how often the theme comes up
This game is genuinely insane with the amount of playtime, play styles, and customizations it offers you. Upgrades and achievements galore. Lore, chaos, and comedy on the side, and awesome songs from a variety of artists. Definitely worth the price. The demo was enough to get me hooked, and checking in on how the game has been dedicatedly expanded since then has only continued to blow me away. Only thing I regret is not putting in a good review sooner.
A serious evolution of the first game. Core mechanic is the same, just a boatload more content, game modes and genuine experimentation and build choices.
good
I don't like the tutorial forcing me to do things, let me play the game at my own pace, I'll discover it when I get there
Very fun game. Lots to do. Multiple game modes and unlocks. Fun synergies
my friend asked my what i was playing and i explained to him i srtaped 3 ani-aircraft cannons and a pistol to a nanobot and went to fight neon microbes, would recomend
If you're a chess player stranded on a desert island with unlimited highspeed internet, and can only play online chess , and your choice of one video game for the rest of your natural and unnatural life, you had better choose Genome Guardian 2. Sorry, DariusBurst Chronicle Saviours, but I have plenty of fish to eat every day already. Sorry, Sektori, but you're competing with chess in score chasing :)
Good
Players by region
Where this game's players are, estimated from review languages.
Related
| Game | Estimated lifetime revenue | Reviews | Review score | Price |
|---|---|---|---|---|
| $141.4K | 770 | 74% | $7.99 | |
| $300.2K | 2.6K | 88% | $4.99 | |
| $159.9K | 327 | 86% | $14.99 | |
| $330 | 2 | 100% | $5.99 | |
| $0 | 66 | 83% | Free | |
| — | 0 | — | — |
Related
| Game | Estimated lifetime revenue | Reviews | Review score | Price |
|---|---|---|---|---|
| $171.8K | 392 | 63% | $19.99 | |
| $171.8K | 724 | 88% | $9.99 | |
| $171.9K | 815 | 90% | $7.99 | |
| $171.9K | 543 | 92% | $19.99 | |
| $171.9K | 340 | 62% | $19.99 | |
| $171.7K | 651 | 25% | $9.99 |